Foreword / Edward Witten -- 1. Where do we come from? What are we? Where are we going? -- 2. The standard model of particle physics -- 3. Why physics is the easiest science -- Effective theories -- 4. Supersymmetry and sparticles -- 5. Testing supersymmetry experimentally -- 6. What is the universe made of? -- 7. Higgs physics -- 8. Some additional help from supersymmetry, and some challenges -- 9. Supersymmetry, string theory, and the primary theory -- 10. Can we really understand the origin of the universe and its natural law(s)? -- App. A. The Standard Model Higgs mechanism -- App. B. The supersymmetry explanation of the Higgs mechanism -- App. C. Charginos and neutralinos -- App. D. Extra dimensions - large extra dimensions?