1. The grand design -- 1.1. The unfolding Universe -- 1.2. Sizes and distances in the Universe -- 1.3. The nature of light and the electromagnetic spectrum -- 1.4. Observing the sky through the Earth's atmosphere -- 1.5. The temperatures of celestial objects -- 1.6. The Universe as observed in different wavebands -- 1.7. The multi-wavelength Universe -- 2. The birth of the stars and the great cosmic cycle -- 2.1. Powering the Sun and the stars -- 2.2. The Sun - a testbed for the physics of the stars -- 2.3. The evolution of stars and the great cosmic cycle -- 2.4. How to observe stars forming -- 2.5. The problems of star formation -- 2.6. Interstellar chemistry and the origin of life -- 3. The origin of quasars -- 3.1. The origins of high energy astrophysics -- 3.2. The radio galaxies and the discovery of quasars -- 3.3. The discovery of pulsars -- 3.4. The supernova SN1987A -- 3.5. The discovery of X-ray binary sources -- 3.6. General relativity and black holes -- 3.7. The astrophysics of black holes -- 3.8. Observational evidence for black holes -- 3.9. The big problems -- 4. The origin of galaxies -- 4.1. The evolution of galaxies oversimplified -- 4.2. Hubble's law and the expansion of the Universe -- 4.3. The dynamics of the expanding Universe -- 4.4. The measurement of cosmological parameters -- 4.5. The dark matter problem -- 4.6. Gravitational lenses and dark matter -- 4.7. The basic problems of galaxy formation -- 4.8. Radiation in the expanding Universe -- 4.9. Dark matter and galaxy formation -- 4.10. Making real galaxies -- 5. The origin of the Universe -- 5.1. Towards the Big Bang -- 5.2. The thermal history of the Universe -- 5.3. The synthesis of the light elements -- 5.4. Nine facts about the Universe -- 5.5. The four fundamental problems -- 5.6. Solutions to the great problems -- 5.7. The anthropic cosmological principle -- 5.8. The inflationary Universe and clues from particle physics -- 5.9. Final things