Includes bibliographical references (pages 161-170) and index.
Pt. 1. Philosophical and scientific problems when applying statistical methods to clinical data -- The randomized controlled clinical trial -- Probability models and clinical medicine -- Significance tests versus hypothesis tests -- Neyman's insights -- Reconciling Fisher and Neyman -- Pt. 2. Techniques for applying restricted tests to data from radomized controlled clinical trials -- Continuous measures taken over time -- Combining data across measures -- Counts of events -- Permutation tests and resampling techniques -- Neyman's restricted Chi square tests -- Miscellaneous methods for increasing power -- Bayesian estimation -- An example of the type of analysis suggested in this book