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Videos, Slides, Films
Biased signaling at mu opioid receptor splice variants
- Author / Creator
- Available as
- Online
Details
- Creator
- Ying-Xian Pan
- Format
- Videos, Slides, Films
- Language
- English
- Publication
-
- London : Henry Stewart Talks, 2020
- Physical Details
-
- 1 videorecording (41 min., 40 sec.) : sound, color
- video file
- Animated audio-visual presentation with synchronized narration.
- Title from title frames.
- Contents: Extensive alternative pre-mRNA splicing of the mu opioid receptor gene (OPRM1) -- Distinct intracellular C-terminal tails in different full-length 7TM C-terminal variants -- Distinct in vivo functions of several C-terminal tails -- In vivo truncation of C-terminal tails encoded by E7 affects morphine tolerance and reward -- In vivo truncation of C-terminal tails encoded by E4 affects morphine tolerance and dependence
Subjects
- Cellular signal transduction.
- G proteins -- Receptors.
- Opioids -- Receptors.
- Alternative Splicing.
Medical Subject Heading
- Drug Tolerance.
Medical Subject Heading
- Morphine.
Medical Subject Heading
- Receptors, G-Protein-Coupled -- metabolism.
Medical Subject Heading
- Receptors, Opioid, mu -- genetics.
Medical Subject Heading
- Receptors, Opioid, mu -- metabolism.
Medical Subject Heading
- Signal Transduction.
Medical Subject Heading