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Videos, Slides, Films
Adeno-associated viruses (AAV)
- Author / Creator
- Available as
- Online
Details
- Creator
- Kenneth I. Berns
- Format
- Videos, Slides, Films
- Language
- English
- Publication
-
- London : Henry Stewart Talks Ltd, 2007
- Physical Details
-
- videorecording (37 min., 34 sec.)
- video file
- Retrieved April 15, 2024, from https://hstalks.com/bs/371/.
- Introduction -- Adeno-associated virus (AAV) -- AAV classification -- AAV is a helper dependent parvovirus -- AAV genetic map -- AAV Rep proteins -- Rep functions -- AAV terminal repeat -- ITR functions -- AAV replication -- Enzymes needed for AAV replication -- AAV infection -- Viral entry -- AAV receptors -- Illustration of AAV infection -- VP1 has phosholipase A2 (PlA2) activity -- Site-specific integration -- TRP-186 -- AAVS1 (19q13.4) -- Features of AAV integration -- AAV for gene therapy -- Ideal vector -- How to make an AAV vector -- Recombinant AAV virus preparation -- How do you make a lot of vectors -- Strategies -- Do recombinant AAV vectors integrate? -- Diseases targets for AAV -- AAV in some clinical trials -- Viral vectors in clinical trials -- AAV features -- Conclusions -- From medical oddity to medical tool!