1 video recording (01 hr., 07 min., 24 sec.) : sound, color
video file
Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: The global immune response of the lungs -- Dendritic cells (DCs): localisation, trafficking, probing for antigen, activation, behaviour in airways during asthma and inflammation -- Controlling responsiveness to the node T cell area & Immunological synapse formation -- Peptide presentation by MHC class II molecules -- Cascade of costimulatory events -- Th2 lymphocytes role in airway inflammation -- Targeting DCs -- Allergen exposure activation -- Epithelial vs. DC expression of TLR4 -- Metabolic alterations -- Uric acid and antigen sensitisation in mice -- DC depletion -- Basement membrane thickening in asthma -- Model of chronic airway remodelling in the lungs -- Collagen deposition & antigen uptake/recognition -- Presentation of neoantigen