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Videos, Slides, Films
Skin epigenetics : how chromatin regulators orchestrate skin functions
- Author / Creator
- Available as
- Online
Details
- Creator
- Vladimir Botchkarev
- Format
- Videos, Slides, Films
- Language
- English
- Publication
-
- London : Henry Stewart Talks, 2014
- Physical Details
-
- 1 videorecording (32 min., 52 sec.) : sound, color
- video file
- Animated audio-visual presentation with synchronized narration.
- Title from title frames.
- Contents: Skin structure, functions and development -- Molecular control of cell differentiation -- What is epigenetics? -- What controls variability of skin phenotypes? -- Genes encoding keratinocyte-specific proteins -- Molecular signature of epidermal layers -- Levels of epigenetic regulation -- DNA methylation and hydroxymethylation -- DNA methylation influence on the epidermis -- Post-translational histone/covalent modifications -- Histone acetylation/de-acetylation -- Polycomb-repressive complex -- Polycomb and Trithorax play antagonistic roles -- ATP-dependent chromatin remodeling -- Non-coding RNA-dependent mechanisms -- Nucleus: storage, replication of genetic material -- Topological gene interactomes -- Morphogenesis of the epidermis -- Epidermal differentiation complex -- EDC and Lor relocation to nuclear interior -- p63 and Brg1 ablation results in retention of EDC -- Genome organizer AT-rich binding Satb1 protein -- Transcription factor and epigenetic mechanisms -- Future directions of epigenetic research
Subjects
- Chromatin
- Epidermis -- Molecular aspects.
- Epigenesis.
- Skin -- Molecular aspects.
- Cell Differentiation.
Medical Subject Heading
- Chromatin Assembly and Disassembly -- genetics.
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- Chromatin -- metabolism.
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- DNA Methylation.
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- Epidermis -- growth & development.
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- Epigenesis, Genetic -- physiology.
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- Gene Expression Regulation, Developmental.
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- Keratinocytes.
Medical Subject Heading
- Protein Processing, Post-Translational.
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- Skin Physiological Phenomena.
Medical Subject Heading
- Skin -- growth & development.
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- Transcription Factors.
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