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Videos, Slides, Films
Therapy in cancer 2008 : quo vadis?
- Author / Creator
- Available as
- Online
Details
- Creator
- Jeffrey W. Clark
- Format
- Videos, Slides, Films
- Language
- English
- Publication
-
- London : Henry Stewart Talks Ltd, 2009
- Physical Details
-
- 1 streaming video file (36 min.) : color, sound
- video file
- Retrieved April 16, 2024, from https://hstalks.com/bs/1112/.
- Introduction -- Overview -- Why are new therapeutic approaches important -- Prevention and screening -- Current cancer therapy: non-surgical -- Most chemotherapy targets DNA -- Chemotherapy effects -- Current state of cancer therapy: Efficacy -- Current state of cancer therapy: Toxicity -- Molecular pathogenesis of cancer -- Pursuing targeted therapy in cancers -- Targeted biologic therapies -- Potential targets in cancer -- Evolving targets and agents -- Shift from chemotherapy to targeted agents -- Clinically established molecular targets -- Targeted therapy: proteins -- Targeted therapy: small molecules -- Changes brought about by targeting: Efficacy -- Changes brought about by targeting: Toxicity -- Biomarkers in drug development (1) -- What is currently known (Biomarkers) -- What research is ongoing (Biomarkers)? -- Example for the use of biomarkers -- What is currently known (Angiogenesis)? -- The VEGF family and its receptors -- VEGF targeted therapy -- Phase 3 trial of bevacizumab in MCRC: Survival -- Biological correlates of bevacizumab -- Does toxicity correlate with response? -- Metastatic CRC -- What research is ongoing (Agents)? -- Sorafenib -- Phase I of sorafenib (DF/HCC, USC) -- Phase I's of sorafenib (pooled) -- Does toxicity correlate with time to progression? -- Phase III trial RCC -- Future directions in cancer treatment options -- Sequencing: same pathways, different mutations -- Core pathways altered in pancreatic cancer -- Core pathways altered in colorectal cancer -- Implications of genetic sequencing of solid tumors -- Pancreatic cancers sequencing -- Epigenetics and cancer therapy -- Conclusions -- Closing remarks