1 videorecording (53 mins., 48 sec.) : sound, color
video file
Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: What is short-term synaptic plasticity? -- Use of quantal analysis to show that plasticity arises presynaptically -- Synaptic depression and the "Depletion Model" -- Relationship of depletion model parameters to binomial statistical parameters -- Refinements to the depletion hypothesis -- Origin of slow phases of depression -- Role of multiple vesicle pools -- Role of vesicle endocytosis -- Role for calcium in recovery -- Why depression is sometimes absent -- Other forms of depression -- Phases of synaptic enhancement: facilitation, augmentation, and potentiation -- Presynaptic electrical events in synaptic enhancement -- Calcium and the nonlinear summation single site hypothesis -- Kinetic components of calcium removal -- Multiple sites of calcium action -- Problems with identifying molecular mediators -- Candidate molecular mediators -- A comprehensive model of presynaptic plasticity -- Other forms of synaptic enhancement -- Computational roles of short-term synaptic plasticity -- Physiological roles of short-term synaptic plasticity