Animated audio-visual presentation with synchronized narration.
Title from title frames.
Updated version of a talk first published in 2013.
Contents: Calcium and Signaling -- Excessive calcium causes cellular stress -- Signaling pathways are turned on to combat this stress -- In budding yeast, these pathways involve nuclear translocation of transcriptional regulator Crz1 -- Examination of this regulator shows that nuclear translocation occurs in "bursts" -- Bursts are quantized and frequency-modulated -- Frequency modulation enables proportional expression of downstream target genes