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Pearls and Pitfalls in Skin Ulcer Management
- Available as
- Online
Details
- Creator
- Michele Maruccia [and three others], editors
- Format
- Books
- Language
- English
- Contributors
- Publication
-
- First edition
- Cham, Switzerland : Springer, [2023]
- ©2023
- Physical Details
-
- 1 online resource (662 pages)
- ISBNs
- 9783031454530, 3031454537, 9783031454523
- Includes bibliographical references.
- Intro -- Preface -- Contents -- Part I: Introduction to Wound Care, Cleasing, Antiseptic and Local Treatment -- 1: Vulnology (Also Known as Wound Care): History and Myths of Chronic Wounds -- References -- 2: Aetiology, Classification and Advocating for a Holistic, Multidisciplinary Approach -- 2.1 Epidemiology -- 2.2 Aetiopathogenesis -- 2.3 Classification -- 2.3.1 Venous Ulcers -- 2.3.2 Arterial Ulcers -- 2.3.3 Diabetic Foot Ulcers -- 2.3.4 Pressure Ulcers -- 2.3.5 Atypical Ulcers -- 2.4 Diagnosis -- 2.5 Multidisciplinary Approach -- 2.6 Conclusions -- References -- 3: Anatomical Base for Diagnosis -- 3.1 Introduction -- 3.2 Classification of Leg Ulcers -- 3.2.1 Venous Ulcers -- 3.2.1.1 Venous Anatomy of the Legs -- 3.2.1.2 Physical Examination -- Edema -- Lipodermatosclerosis -- Atrophie Blanche -- Stasis Dermatitis -- Pigmented Purpuric Dermatosis -- Exudate -- 3.2.2 Arterial Leg Ulcers -- 3.2.3 Diabetic Ulcers -- 3.2.4 Uncommon Type of Ulcers -- 3.2.4.1 Hematological Ulcers -- 3.2.4.2 Martorell's Ulcer -- 3.2.4.3 Lymphatic Ulcers -- 3.3 Differential Diagnosis Based on Clinical Features -- 3.3.1 Localization -- 3.3.2 Size of Ulcers -- 3.3.3 Symptoms -- References -- 4: Wound Hygiene: From Traditional to Microenvironment in Cleansing -- References -- 5: Principles of Antiseptic Treatments -- 5.1 Definition of Antisepsis -- 5.2 History of Antisepsis -- 5.3 Definition of Antiseptic Agent -- 5.4 The Bioburden in Skin and Wounds -- 5.5 Characteristics of Antiseptics -- 5.6 Indication of Antiseptic Treatment -- 5.6.1 Antiseptics in Surgery -- 5.6.2 Antiseptics in Wound Healing -- 5.7 Characteristics of Commonly Used Antiseptics -- 5.7.1 Chlorhexidine -- 5.7.2 Povidone-Iodine -- 5.7.3 Polyhexamethylene Biguanide -- 5.7.4 Silver -- 5.7.5 Hydrogen Peroxide -- 5.7.6 Superoxidized Solutions -- 5.7.7 Honey
- 5.8 Conclusions -- References -- 6: The TIMEH Protocol -- References -- Part II: Dressing and Bandages -- 7: Ulcer Debridement -- 7.1 Debridement Overview -- 7.2 Autolytic Debridement -- 7.3 Enzymatic Debridement -- 7.4 Biological Debridement -- 7.5 Mechanical Debridement -- 7.5.1 Wound Irrigation -- 7.5.2 Pulsed Lavage -- 7.6 Sharp Debridement -- 7.7 Surgical Debridement -- 7.7.1 Hydrosurgery -- 7.8 Other Types of Debridement -- 7.8.1 Ultrasound Debridement -- 7.8.2 Laser Debridement -- 7.9 Factors to Consider in Choosing the Debridement Method -- References -- 8: Advanced Moist Wound Dressing: Classification by Function -- 8.1 Classification by Function "Status-Based" -- 8.1.1 Dressings that Promote Autolysis and Debridement -- 8.1.2 Dressings that Promote Granulation Tissue -- 8.1.2.1 Homeostasis of Fluids -- 8.1.2.2 Bio-Induction -- 8.1.3 Antimicrobial Dressings -- 8.1.4 Re-Epithelializing Eudermal Dressings -- 8.2 Symptom-Based Dressings -- 8.3 Conclusions -- References -- 9: Dressing: Indications on Applications -- 9.1 Introduction -- 9.2 Types of Wound Dressings -- 9.2.1 Gauze -- 9.2.2 Impregnated Gauze -- 9.2.3 Film -- 9.2.4 Hydrogel -- 9.2.5 Hydrocolloid -- 9.2.6 Foam -- 9.2.7 Alginate -- 9.2.8 Hydrofiber -- 9.2.9 Silver -- 9.2.10 Iodine -- 9.2.11 Tissue-Engineered Biological Dressings -- 9.2.11.1 Non-Living Skin Substitutes -- 9.2.11.2 Living Skin Substitutes -- 9.2.12 Other Types of Dressings -- 9.3 Negative Pressure Wound Therapy (NPWT) -- 9.4 Conclusions -- References -- 10: Dressing in Burns -- 10.1 Introduction -- 10.2 Full-Thickness Burns -- 10.2.1 Skin Substitutes -- 10.3 Partial-Thickness Burns -- 10.3.1 Superficial Burns -- 10.3.2 Superficial Partial-Thickness Burns -- 10.3.3 Blister Management -- 10.3.4 Hydrogel Dressings -- 10.3.5 Hydrofiber Dressings -- 10.3.6 Alginates
- 10.4 Deep Partial-Thickness Burns -- 10.5 Facial Burns -- 10.5.1 Burn Cleansing -- 10.6 Chemical Burns -- References -- 11: Innovative Dressings -- 11.1 TLC-NOSF Technology-Based Dressings -- 11.2 Hydroactive Dressings, Gelling Fiber Dressings, and 3D FIT Technology Dressings -- 11.3 Dressings with Hydrofiber and More Than Silver Technology -- 11.3.1 PluroGel® Burn and Wound Dressing -- 11.3.2 PluroGel® Burn and Wound Dressing with PSSD -- 11.3.3 Issue-Targeting Dressings -- 11.3.4 Activated Carbon-Based Dressings -- 11.4 Copper Antimicrobial Dressings -- 11.4.1 Dialkylcarbamoyl Chloride (DACC) Technology -- 11.5 Primary Wound Dressing Spray -- References -- 12: Compression Therapy in Ulcer Care -- 12.1 Introduction -- 12.1.1 Evidence-Based Compression Therapy -- 12.1.2 Elastic and Inelastic Materials -- 12.1.3 Which Compression Material for Ulcer Treatment? -- 12.1.4 Comparing Compression Materials -- 12.1.5 Compression Therapy and Venous Hemodynamics -- 12.1.6 Is Inelastic Compression Always Mandatory for Ulcer Treatment? -- 12.1.7 Ulcer Recurrence Prevention -- 12.2 Special Circumstances -- 12.2.1 Compression Therapy and Mixed Leg Ulcers -- 12.2.2 Compression Therapy in Vasculitic Ulcers -- 12.2.3 Elastic or Inelastic Bandages in Patients with Leg Ulcers and Restricted Mobility? -- 12.2.4 Contraindications to Compression Therapy -- 12.3 Conclusions -- References -- Part III: Instrumental Treatments in Wounds -- 13: Scientific Principles and Clinical Application of Negative Pressure Wound Therapy (NPWT) -- 13.1 The Mechanisms of Action -- 13.2 The Possible Clinical Indications -- References -- 14: Latest Applications of Negative Pressure Wound Therapy -- 14.1 Latest Applications of Negative Pressure Wound Therapy (NPWT) -- 14.1.1 Diabetic Foot -- 14.1.2 Pressure Ulcer Reconstruction
- 14.1.3 Flaps Venous Congestion -- 14.1.4 NPWT Prophylactically on Closed Incisional Wounds -- 14.2 New Perspectives -- 14.2.1 Breast Peri-Prosthesis Infection and NPTW -- 14.2.2 Fat Grafting and NPTW -- 14.3 Conclusions -- References -- 15: Electrical Stimulation in Wound Care -- 15.1 Direct Currents -- 15.1.1 Low-Intensity Direct Current (LIDC) -- 15.2 Alternating and Pulsed Currents -- 15.2.1 Low-Intensity Pulsed Direct Current (LIPDC) -- 15.2.2 High-Voltage Pulsed Current (HVPC) -- 15.2.3 Simulated Biphasic ES (SSES) -- 15.2.4 Asymmetric Biphasic Electrical Stimulation -- 15.2.5 Symmetric Biphasic Electrical Stimulation (SBES) -- 15.3 Stochastic Currents -- 15.3.1 Decubitus Direct Current Treatment (DDTC) -- 15.3.2 Frequency Rhythmic Electrical Modulation System (FREMS) -- References -- 16: Phototherapy in Wound Care -- References -- 17: Laser in Wound Care -- 17.1 Laser in Wound Care -- 17.2 Debridement Laser -- 17.3 Biostimulation Lasers -- References -- 18: Treatment of Chronic Wounds and Ulcers with Focused and Defocused Shock Waves -- 18.1 Introduction -- 18.2 Shock Waves -- 18.3 Aspects of Technology -- 18.4 The Biological Stimulus of the Shock Wave -- References -- 19: Hydrosurgery in Wound Care -- References -- 20: Ultrasound in Wound Care -- 20.1 Introduction -- 20.2 Device Characteristics -- 20.3 Mechanism of Action -- 20.4 Therapeutical Effects of Ultrasound on Chronic Wounds -- 20.5 Ultrasound Application in Relation to Different Wound Healing Phases -- 20.5.1 Inflammatory Phase -- 20.5.2 Proliferative Phase -- 20.5.3 Maturation or Remodeling -- 20.6 Treatment Protocols -- References -- 21: Topical Oxygen in Wound Care -- 21.1 Introduction -- 21.2 Topical Oxygen Therapy: Clinical Trials -- 21.3 Topical Oxygen Therapy and Debridement -- 21.4 Topical Oxygen Therapy and Cost-Effectiveness
- 21.5 Retrospective Study -- 21.6 Cases (Courtesy of the Wound Care Unit, Kuala Lumpur Hospital) -- 21.7 Conclusion -- References -- Part IV: Regenerative Medicine and Tissue Bioingeneering -- 22: Evidence-Based and Clinical Experimentation on Cell Therapy -- 22.1 Background -- 22.2 Cells Suitable for Cell Therapy -- 22.2.1 Pluripotent Stem Cells -- 22.2.2 Embryonic and Extraembryonic Stem Cells -- 22.2.3 Adult Stem Cells -- 22.3 Evidence on Applicability of Cell Therapy in Ulcer Management -- References -- 23: Bioinductive Dressing -- 23.1 Introduction -- 23.2 Bioactive -- 23.2.1 Bioactive Dressings -- 23.2.2 Drug-releasing dressings -- 23.3 Drug-Loaded Wound Dressing -- 23.3.1 Collagen -- 23.3.2 Biosynthesis and Degradation -- 23.3.3 Collagen & -- Tissue Repair -- 23.3.3.1 Anti-Inflammatory Action -- 23.3.3.2 Neoangiogenic Action -- 23.3.3.3 Role in ECM Remodeling -- 23.3.3.4 Dressings -- 23.3.3.5 Hyaluronic Acid -- 23.3.3.6 Honey -- 23.4 Honey and its Properties -- 23.4.1 Antibacterial Activity -- 23.4.2 Anti-Inflammatory Activity -- 23.4.3 Antioxidant Activity -- 23.4.4 Promoter of Wound Debridement -- 23.4.5 Neoangiogenesis Promoter -- 23.4.6 Promoter of Immune System Response -- 23.4.6.1 Healing Promoter -- 23.4.6.2 Limits to Use and Side Effects -- 23.4.6.3 The Dressings -- 23.4.7 Effects on Different Types of Wounds -- 23.4.7.1 Chronic Ulcers -- 23.4.7.2 Burns -- 23.4.7.3 Surgical Wounds -- 23.4.7.4 Ozonids -- 23.4.7.5 Mesoglycan -- 23.4.7.6 DNA and Ribosomes -- 23.4.7.7 Rigenase® -- 23.4.7.8 Dressings -- 23.4.7.9 MMPs Inhibitors -- References -- 24: Skin Substitutes -- 24.1 Introduction -- 24.2 Characteristics and Composition -- 24.3 Classifications -- 24.4 Main Skin Substitutes on the Market -- 24.5 Clinical Overview -- References -- 25: Mesenchymal Cells from Adipose Tissue
- 25.1 Introduction