Front Cover -- HANDBOOK OF OBJECT NOVELTY RECOGNITION -- HANDBOOK OF OBJECT NOVELTY RECOGNITION -- Copyright -- Contents -- Contributors -- Preface -- References -- 1 - Object Novelty Recognition Memory -- 1. INTRODUCTION -- 2. OBJECT NOVELTY RECOGNITION MEMORY TEST USES -- 3. DIVERSITY AND EXPLOITATION OF TEST PARAMETERS -- 4. PLURALITY AND AMBIGUITY OF THE OBJECT NOVELTY RECOGNITION MEMORY TEST IDENTIFIERS -- 5. OBJECT RECOGNITION AND WORKING MEMORY -- 6. OBJECT NOVELTY RECOGNITION MEMORY TEST AND VARIANTS -- 7. OPEN FIELD AND MAZES -- 8. OBJECT FEATURES -- 8.1 Visual Features -- 8.2 Visual Stimuli Affordances -- 8.3 Automated Visual Discrimination and Recognition Memory -- 9. SIMPLE VERSUS COMPLEX OBJECTS VERSUS SIMILARITY -- 10. SINGLE OBJECT AND DIFFERENT OBJECT IN THE SAMPLE PHASE -- 10.1 Single Object -- 10.2 Different Objects -- 11. LOCOMOTOR ACTIVITY, EXPLORATION AND MEMORY -- 12. PRETEST HABITUATION -- 13. MEASUREMENTS AND ANALYSIS -- 13.1 Object Contacts and Object Zones -- 13.2 Indices of Object Exploration and Discrimination -- 14. CONCLUSION -- References -- 2 - Theories and Concepts -- 1. INTRODUCTION -- 1.1 Declarative Memory: Episodic and Semantic Memory -- 1.2 Short-Term Versus Long-Term Versus Working Memory -- 1.3 Recognition Memory: Recollection and Familiarity -- 2. NEUROANATOMY OF THE MEDIAL TEMPORAL LOBE -- 3. THEORIES OF HIPPOCAMPAL MEMORY FUNCTION -- 3.1 The Standard Model of Consolidation or Declarative Memory Theory -- 3.2 The Spatial Map Theory -- 3.3 The Relational Theory -- 3.4 The Multiple Trace Theory -- 3.5 The Dual-Process Theory -- 4. FAMILIARITY AND RECOLLECTION -- 4.1 Human Studies on Recognition Memory Performance -- 4.2 Animal Studies on Recognition Memory Performance -- 5. OBJECT PERCEPTION AND RECOGNITION -- 6. SPATIAL PERCEPTION AND RECOGNITION -- 7. TEMPORAL PERCEPTION AND RECOGNITION
8. TOWARDS A UNIFYING MODEL OF RECOGNITION AND RECALL -- 8.1 What/Where/When -- 8.2 Familiarity Versus Recollection -- 8.3 Medial Temporal Lobe Versus Prefrontal Cortex -- 8.4 Unifying Neuropsychobiological Framework -- 9. CONCLUSIONS -- Acknowledgements -- References -- 3 - Object Novelty Memory Tests: Methods, Test Procedures and Measurements -- 1. OBJECT NOVELTY RECOGNITION -- 1.1 General -- 1.2 Apparatus -- 1.3 Procedure -- 1.4 Statistical Analysis -- 1.5 Familiarization and Habituation -- 2. OBJECT LOCATION RECOGNITION -- 2.1 General -- 2.2 Apparatus -- 2.3 Procedure -- 2.4 Statistical Analysis -- 2.5 Familiarization and Habituation -- 3. OBJECT IN PLACE RECOGNITION -- 3.1 General -- 3.2 Apparatus -- 3.3 Procedure -- 3.4 Statistical Analysis -- 3.5 Familiarization and Habituation -- 4. OBJECT IN CONTEXT RECOGNITION -- 4.1 General -- 4.2 Apparatus -- 4.3 Procedure -- 4.4 Statistical Analysis -- 4.5 Familiarization and Habituation -- 5. OBJECT TEMPORAL ORDER RECOGNITION -- 5.1 General -- 5.2 Apparatus -- 5.3 Procedure -- 5.4 Statistical Analysis -- 5.5 Familiarization and Habituation -- 6. OBJECT PATTERN SEPARATION -- 6.1 General -- 6.2 Apparatus -- 6.3 Procedure -- 6.4 Statistical Analysis -- 6.5 Familiarization and Habituation -- 7. CONCLUSIONS -- Acknowledgements -- References -- 4 - The Mouse Visual System and Visual Perception -- 1. Historical Perspective -- 2. Overview of central visual pathways -- 3. Eyes and Retina -- 4. Superior Colliculus -- 5. The First-Order Visual Thalamic Relay: dLGN -- 6. Primary Visual Cortex and Higher Visual Areas -- 7. Role of Visual Cortex -- 8. Top-Down Connections to Mouse V1 -- References -- 5 - Methodological Approaches to the Behavioural Investigation of Visual Perception in Rodents -- 1. INTRODUCTION -- 1.1 Organization of the Chapter -- 2. APPROACHES BASED ON COLLECTION OF SPONTANEOUS RESPONSES
2.1 Tests of Spontaneous Object Recognition -- 2.1.1 Limitations of Standard Spontaneous Object Recognition Tasks -- 2.1.2 Improved Variants of Spontaneous Object Recognition Tasks -- 2.2 Spontaneous Responses in Ethological Contexts -- 2.3 Navigation in Virtual Environments -- 3. APPROACHES BASED ON EXPLICITLY TRAINING RODENTS IN VISUAL DISCRIMINATION TASKS -- 3.1 One Stimulus - One Choice Design (Go/No-Go Task) -- 3.2 Two Stimuli - Two Choices Design (2-Stim/2-Choices) -- 3.3 One Stimulus - Two Choices Design (1-Stim/2-Choices) -- 4. ADVANCED PSYCHOPHYSICAL PROCEDURES -- 4.1 Configural Visual Discrimination Tasks -- 4.2 Classification Image Approaches -- 4.3 Visual Priming Paradigms -- Acknowledgements -- References -- 6 - Exploiting Novelty and Oddity Exploratory Preferences in Rodents to Study Multisensory Object Memory and Perception -- 1. INTRODUCTION -- 1.1 Multisensory Object Processing in Animals -- 2. DEVELOPMENT OF MULTISENSORY OBJECT PROCESSING TASKS FOR RODENTS -- 2.1 Crossmodal Object Recognition Task -- 2.2 General Procedure for the Crossmodal Object Recognition Task -- 2.2.1 Mouse Adaptation -- 2.2.2 Control Tasks and Other Considerations -- 2.3 CMOR With Preexposure -- 2.3.1 Control Tasks and Considerations -- 2.4 Multisensory Object Oddity -- 2.5 General Procedure for the Multisensory Oddity Task -- 2.5.1 Mouse Adaptation -- 2.5.2 Unimodal Oddity Control Tasks -- 3. NEUROBIOLOGY OF RODENT CROSSMODAL OBJECT RECOGNITION -- 3.1 Posterior Parietal Cortex -- 3.2 Perirhinal Cortex -- 3.3 Cortical Interactions -- 3.4 Retrosplenial Cortex -- 3.5 Hippocampus -- 3.6 Prefrontal Cortex -- 3.7 Neurotransmitter Systems Implicated in Crossmodal Cognition -- 3.7.1 Acetylcholine -- 3.7.2 GABA -- 4. CLINICAL RELEVANCE OF RODENT MULTISENSORY OBJECT PROCESSING TASKS -- 4.1 Schizophrenia -- 4.2 Alzheimer's Disease -- 5. CONCLUSIONS -- References
7 - Variants of the Spontaneous Recognition Procedure Assessing Multisensory Integration Reveal Behavioral Alterati ... -- 1. INTRODUCTION -- 2. MULTISENSORY INTEGRATION IN PSYCHIATRIC DISORDERS -- 2.1 Schizophrenia -- 2.2 Autism -- 2.3 Depression and Anxiety -- 2.4 Neurological Disorders -- 3. RODENT TASKS -- 3.1 Cross-modal Object Recognition -- 3.2 Oddity Tasks -- 4. MULTISENSORY INTEGRATION OBJECT RECOGNITION DEFICITS IN RODENT MODELS OF PSYCHIATRIC AND NEUROLOGICAL DISORDERS -- 5. CONCLUSIONS AND FUTURE DIRECTIONS -- 5.1 Research Domain Criteria: A Theoretical Framework for Future Research on Multisensory Integration in Brain Disorders -- References -- 8 - Visual Object Recognition Task: A Translational Paradigm to Evaluate Sustained Attention Across Species -- 1. INTRODUCTION -- 2. FROM NOVEL OBJECT RECOGNITION TO VIRTUAL OBJECT RECOGNITION TASK -- 2.1 Zebrafish and Mice Discriminate Between Moving and Stationary Shape Stimuli -- 2.2 The Use of VORT in Different Inbred Strains and Knockout Mice -- 3. CONCLUSIONS -- Glossary -- References -- 9 - Object Novelty and Object Location Recognition Memory in Fish - Recent Advances -- 1. INTRODUCTION -- 2. NOVEL OBJECT RECOGNITION TESTING IN FISH -- 2.1 Object Choice -- 2.2 Habituation, Trial Length, Retention Interval -- 3. EPISODIC-LIKE MEMORY TESTING IN FISH -- 3.1 Episodic-Like Memory' Tests Based on Food Reinforced Response -- 3.2 Memory Tests Based on Animals' Spontaneous Response -- 4. CONCLUSION -- Acknowledgements -- References -- 10 - Integration of Human Eye-Tracking Responses and Object Recognition Test Performance -- 1. INTRODUCTION -- 2. THE NOVEL IMAGE NOVEL LOCATION TEST -- 3. USE OF THE NINL TEST AND COMPARISON OF NINL TEST PERFORMANCE IN HUMANS WITH THAT OF OBJECT RECOGNITION IN MICE -- 4. INTEGRATION OF EYE-TRACKING AND NINL TEST PERFORMANCE
5. RELATIONSHIP BETWEEN INTEGRATION OF EYE-TRACKING RESPONSE AND NINL PERFORMANCE MEASURES TO PERFORMANCE ON THE RAVEN'S FLUID ... -- 6. CONCLUSIONS -- References -- 11 - Developmental Trajectories of Object and Spatial Recognition Memory in Infant Rhesus Macaques -- 1. INTRODUCTION -- 2. AN EARLY DEVELOPING OBJECT RECOGNITION SYSTEM -- 2.1 Role of the Medial Temporal Lobe Structures on Object Recognition -- 2.2 Developmental Trajectory of Object Recognition Memory -- 2.3 Impact of Neonatal Medial Temporal Lobe Lesions -- 3. PROTRACTED MATURATION OF SPATIAL RECOGNITION MEMORY -- 3.1 Role of the Medial Temporal Lobe Structures on Spatial Recognition Memory -- 3.1.1 Memory for Spatial Location -- 3.1.2 Memory for Object-Place Associations -- 3.2 Spatial Location Memory Emerges Earlier Than Object-In-Place Memory -- 3.3 Impact of Neonatal Hippocampal Lesions on the Emergence of Spatial Memory -- 3.3.1 Memory for Locations -- 3.3.2 Memory for Object-Place Associations -- 4. RELATIONSHIPS TO HUMAN MEMORY DEVELOPMENT -- Funding Sources -- References -- 12 - Perirhinal Cortex Lesions and Spontaneous Object Recognition Memory in Rats: Detecting Novelty But Not Disting ... -- 1. INTRODUCTION -- 2. SPONTANEOUS OBJECT RECOGNITION MEMORY AND THE PERIRHINAL CORTEX -- 3. ISSUES OF EXPLORATION AND HABITUATION -- 4. THE LEVEL OF EXPLORATION PARADOX -- 5. THE BOW-TIE MAZE -- 6. THE BOW-TIE MAZE, PERIRHINAL CORTEX LESIONS, LEVELS OF EXPLORATION, AND HABITUATION -- 7. THE BOW-TIE MAZE, PERIRHINAL CORTEX LESIONS, AND INTERFERENCE -- 8. NOVELTY DISCRIMINATION VERSUS NOVELTY DETECTION -- 9. FUTURE DIRECTIONS -- Acknowledgements -- References -- 13 - Using the Spontaneous Object Recognition Memory Tasks to Uncover the Neural Circuitry of Recognition Memory: T ... -- 1. INTRODUCTION -- 2. THALAMUS AND RECOGNITION MEMORY
2.1 The Effects of Damage to the Thalamic Nuclei: Evidence From Clinical Studies