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Handbook of immunoassay technologies : approaches, performances, and applications
- Available as
- Online
Details
- Creator
- edited by Sandeep K. Vashist, John H. T. Luong
- Format
- Books
- Language
- English
- Contributors
- Publication
-
- London, England : Academic Press, 2018
- ©2018
- Physical Details
-
- 1 online resource (479 pages) : illustrations (some color)
- ISBNs
- 012811794X, 9780128117941, 9780128117620, 0128117621
- OCLC
- on1018307534
- Includes bibliographical references at the end of each chapters and index.
- Front Cover -- Handbook of Immunoassay Technologies -- Handbook of Immunoassay Technologies: Approaches, Performances, and Applications -- Copyright -- Contents -- Contributors -- Preface -- OBJECTIVES OF THE BOOK -- SCOPE OF THE BOOK -- TARGET AUDIENCE -- BOOK ORGANIZATION -- 1 - Immunoassays: An Overview -- 1. OVERVIEW OF IMMUNOASSAYS -- 2. ANTIBODY STRUCTURE -- 3. NEED FOR IMMUNOASSAYS -- 3.1 Clinical -- 3.2 Industrial -- 3.3 Environment and Security -- 3.4 Food -- 3.5 Personalized Healthcare -- 4. IMMUNOASSAY FORMATS -- 5. CONCLUSIONS AND FUTURE TRENDS -- REFERENCES -- 2 - Antibody Immobilization and Surface Functionalization Chemistries for Immunodiagnostics -- 1. INTRODUCTION -- 2. SURFACE FUNCTIONALIZATION CHEMISTRIES -- 2.1 Hydroxyl Groups -- 2.2 Amino Groups -- 2.3 Carboxyl Groups -- 2.4 Sulfhydryl Groups -- 2.5 Epoxy Groups -- 3. ANTIBODY IMMOBILIZATION CHEMISTRIES -- 3.1 Covalent -- 3.2 Oriented -- 3.3 Noncovalent -- 3.3.1 Adsorption -- 3.3.2 Affinity -- 3.4 Site-Specific -- 3.5 Peptide Nucleic Acid and Deoxyribonucleic Acid-Directed -- 3.6 Recombinant Antibody -- 4. SURFACE CHARACTERIZATION -- 5. CONCLUSIONS, CHALLENGES, AND FUTURE TRENDS -- REFERENCES -- 3 - Monoclonal Antibody Generation by Phage Display: History, State-of-the-Art, and Future -- 1. INTRODUCTION -- 1.1 History of the Development of Antibody Phage Display -- 1.2 Antibody Formats Used for Phage Display -- 1.3 Further Recombinant Antibody Formats -- 2. PHAGE DISPLAY SELECTION -- 2.1 Advantages of Recombinant Antibody Selection -- 2.2 Guided Selection -- 2.3 Affinity Improvement -- 2.4 Other Selection Technologies -- 3. ANTIBODY LIBRARIES -- 3.1 Immune Libraries -- 3.2 Naïve Natural Libraries -- 3.3 Naïve Semisynthetic Libraries -- 3.4 Naïve Synthetic Libraries -- 3.5 Special Library Designs -- 3.6 Synthetic Libraries From Nonhuman Species
- 4. IN VITRO SELECTION OF ANTIBODIES FOR SPECIFIC APPLICATIONS -- 4.1 Tissue Panning for Immunohistochemistry Antibodies -- 4.2 Sandwich Pair Selection, Complex-Specific Antibodies, and Drug Monitoring -- 4.3 Fully Human Controls in Diagnostic Immunoassays -- 4.4 Site-Specific Conjugation -- 5. CONCLUSION AND OUTLOOK -- 5.1 Future -- REFERENCES -- 4 - Bioanalytical Requirements and Regulatory Guidelines for Immunoassays -- 1. INTRODUCTION -- 2. BIOANALYTICAL REQUIREMENTS FOR AN IMMUNOASSAY -- 2.1 Accuracy -- 2.2 Precision -- 2.3 Selectivity -- 2.4 Sensitivity -- 2.5 Reproducibility -- 2.6 Stability -- 2.7 Recovery -- 2.8 Calibration Curve -- 2.9 Bioanalytical Performance Parameters -- 2.9.1 Limit of Blank -- 2.9.2 Limit of Detection -- 2.9.3 Limit of Quantification -- 2.9.4 Lower Limit of the Linear Interval -- 2.9.5 Lower Limit of the Measuring Interval -- 2.9.6 Errors -- 2.9.7 Carryover -- 2.9.8 Interference -- 2.9.9 Quality Controls -- 2.9.10 Linear Range -- 2.9.11 Analytical Measurement Range -- 2.9.12 Clinically Reportable Range -- 2.9.13 Bias -- 2.9.14 Hook Effect -- 2.9.15 Method Comparison -- 2.9.16 Cross-reactivity -- 3. CRITIQUES AND OUTLOOK -- 4. CONCLUSIONS -- REFERENCES -- 5 - Enzyme-Linked Immunoassays -- 1. INTRODUCTION -- 2. CONVENTIONAL ENZYME-LINKED IMMUNOASSAYS -- 2.1 Enzyme-Linked Immunosorbent Assay -- 2.1.1 Direct Enzyme-Linked Immunosorbent Assay -- 2.1.2 Indirect Enzyme-Linked Immunosorbent Assay -- 2.1.3 Sandwich Enzyme-Linked Immunosorbent Assay -- 2.2 Competitive Enzyme-Linked Immunoassay -- 3. EMERGING ENZYME-LINKED IMMUNOASSAYS -- 3.1 High-Sensitivity Sandwich Enzyme-Linked Immunoassay -- 3.2 Highly Simplified Rapid Sandwich Enzyme-Linked Immunoassay -- 3.3 Wash-Free Immunoassays -- 3.4 Multiplex Immunoassays -- 3.5 Nano/Micromaterial-Based Enzyme-Linked Immunoassay -- 3.6 Paper-Based Enzyme-Linked Immunoassay
- 3.7 Microfluidics-Based Enzyme-Linked Immunoassay -- 3.7.1 Optimiser Enzyme-Linked Immunosorbent Assay -- 3.7.2 Centrifugal Microfluidics-Based Immunoassay -- 3.8 Smartphone-Based Enzyme-Linked Immunoassay -- 4. PORTABLE ANALYZER-BASED IMMUNOASSAYS -- 5. CRITIQUES AND OUTLOOK -- 6. CONCLUSIONS -- REFERENCES -- 6 - Surface Plasmon Resonance-Based Immunoassays: Approaches, Performance, and Applications -- 1. INTRODUCTION -- 1.1 Surface Plasmon Resonance -- 1.2 Surface Plasmon Resonance Principles -- 1.3 Surface Plasmon Resonance-Based Biosensor Platforms -- 2. SURFACE PLASMON RESONANCE-BASED IMMUNOASSAYS -- 2.1 Antibody Introduction -- 2.2 Antibody Screening Using Surface Plasmon Resonance -- 2.3 Surface Plasmon Resonance Immunoassay Introduction -- 2.3.1 Small Molecular Weight Targets -- 2.3.2 Pathogens and Viruses -- 2.3.3 Disease Targets -- 3. FUTURE TRENDS IN SURFACE PLASMON RESONANCE-BASED IMMUNOASSAYS -- 3.1 Surface Plasmon Resonance-Mass Spectrometry -- 3.2 Surface Plasmon Resonance-Point-of-Care Applications -- 3.2.1 CD-Based Surface Plasmon Resonance -- 3.2.2 Mobile Phone-Surface Plasmon Resonance -- 4. CONCLUSIONS -- ACKNOWLEDGMENTS -- REFERENCES -- 7 - Lateral Flow Immunoassays -- 1. INTRODUCTION -- 1.1 Lateral Flow Immunoassays -- 1.1.1 History of the Technology -- 1.1.2 Basic Technology -- 1.1.3 Recognition Elements -- 1.1.4 Signal Labels -- 1.1.5 Storage of Lateral Flow Devices -- 2. ADVANCES IN LATERAL FLOW IMMUNOASSAYS -- 2.1 Coupling to a Range of Detection Principles -- 2.2 Multianalyte and Quantitative Lateral Flow Immunoassays -- 2.3 Reading MultiSpot Lateral Flow Assays -- 2.3.1 Lateral Flow Reader for Microarrays -- 2.3.2 Real-Time Video Reader -- 2.3.3 Reading Arrays by a Smartphone Application -- 3. CHALLENGES AND FUTURE DIRECTIONS -- 3.1 Updated SWOT Analysis -- 3.1.1 Weaknesses -- 3.1.2 Opportunities -- 3.1.3 Threats
- 3.2 Combination With Amplification Procedures -- 3.3 Integration of Lateral Flow Immunoassays With Paper Diagnostics -- 4. BIBLIOGRAPHIC AND COMMERCIAL DATA -- 5. CONCLUSIONS -- REFERENCES -- 8 - Paper-Based Immunoassays -- 1. PAPER-BASED IMMUNOASSAYS: STRATEGIES AND DETECTION PRINCIPLES -- 1.1 Colorimetric Method -- 1.1.1 AuNPs -- 1.1.2 Enzymes -- 1.1.3 Carbon Nanoparticles -- 1.1.4 Magnetic Nanoparticles -- 1.2 Thermal Method -- 1.3 Electrochemical Method -- 1.4 Magnetic Method -- 2. DEVELOPMENT OF THE PAPER-BASED IMMUNOASSAYS DEVICES -- 2.1 Sensitivity Improvement -- 2.2 Automatic Detections -- 2.3 Semiquantification Detection and Quantification Detection -- 3. CONCLUSIONS -- REFERENCES -- 9 - Acoustic Wave-Based Immunoassays -- 1. INTRODUCTION -- 2. CLINICAL DIAGNOSTICS -- 2.1 Quartz Crystal Microbalance Immunosensors -- 2.1.1 Direct Immunosensors -- 2.1.2 Indirect Immunosensors -- 2.1.3 Sandwich-Amplified Immunosensors -- 2.2 Surface Acoustic Wave Immunosensors -- 2.2.1 Direct Immunosensors -- 3. DETECTION OF MICROBIAL PATHOGENS AND TOXINS -- 3.1 Quartz Crystal Microbalance Immunosensors -- 3.1.1 Direct Immunosensors -- 3.1.2 Indirect Immunosensors -- 3.1.3 Sandwich-Amplified Immunosensors -- 3.2 Surface Acoustic Wave Immunosensors -- 3.2.1 Direct Immunosensors -- 3.2.2 Sandwich-Amplified Immunosensors -- 4. DETECTION OF PARASITES -- 4.1 Quartz Crystal Microbalance Immunosensors -- 4.1.1 Direct Immunosensors -- 4.1.2 Indirect Immunosensors -- 4.1.3 Sandwich-Amplified Immunosensors -- 5. DETECTION OF VIRUSES -- 5.1 Quartz Crystal Microbalance Immunosensors -- 5.1.1 Direct Immunosensors -- 5.1.2 Indirect Immunosensors -- 5.1.3 Sandwich-Amplified Immunosensors -- 5.2 Surface Acoustic Wave Immunosensors -- 6. QUARTZ CRYSTAL MICROBALANCE AND SURFACE ACOUSTIC WAVE-BASED ELECTRONIC NOSES
- 7. QUARTZ CRYSTAL MICROBALANCE AND SURFACE ACOUSTIC WAVE IMMUNOASSAYS IN ENVIRONMENTAL MONITORING AND ALLERGENS DETECTION -- 8. INTEGRATED ACOUSTIC WAVE IMMUNOSENSORS FOR POINT OF CARE -- 9. COMMERCIAL ACOUSTIC WAVE IMMUNOSENSORS -- 10. MARKET POTENTIAL AND CONCLUSIONS -- ACKNOWLEDGMENTS -- REFERENCES -- 10 - Interferometry-Based Immunoassays -- 1. INTRODUCTION: GENERAL CONTEXT -- 2. PRINCIPLES OF OPERATION -- 2.1 Label-Free Optical Sensing -- 2.2 Interferometric Sensors -- 3. SENSOR SURFACE FUNCTIONALIZATION -- 3.1 Chemical Activation of Transducers -- 3.2 Immobilization of Recognition Molecules -- 3.3 Elimination of Nonspecific Binding -- 4. APPLICATION OF INTERFEROMETRIC IMMUNOSENSORS -- 4.1 Mach-Zehnder Interferometers -- 4.2 Young Interferometers -- 4.3 Bimodal Interferometers -- 5. CONCLUSIONS AND FUTURE PERSPECTIVES -- REFERENCES -- 11 - Nanomaterial- and Micromaterial-Based Immunoassays -- 1. INTRODUCTION -- 2. MICROMATERIAL-BASED IMMUNOASSAY -- 2.1 Fluorescent Polystyrene Microsphere -- 2.2 Magnetic Microbeads -- 2.3 Nanomaterial-Based Immunoassay -- 3. COLORIMETRIC IMMUNOASSAY -- 3.1 Lateral Flow Assay -- 3.2 Plate-Based Colorimetric Immunoassay -- 4. ELECTROCHEMICAL IMMUNOASSAY -- 5. FLUORESCENT IMMUNOASSAY -- 5.1 Heterogeneous Immunoassay -- 5.2 Fluorescence Resonance Energy Transfer Assay -- 6. CONCLUSION -- REFERENCES -- 12 - Microcantilever-Based Sensors -- 1. INTRODUCTION -- 2. MICROCANTILEVERS AND THEIR MODES OF OPERATION -- 2.1 Operating Modes for Cantilever Mass Sensors -- 3. DETECTION METHODS -- 3.1 Optical -- 3.2 Piezoresistive -- 3.3 Capacitive -- 3.4 Piezoelectric -- 3.5 Interferometry -- 3.6 Optical Diffraction Grating -- 3.7 Charge-Coupled Device -- 4. BENDING BEHAVIOR OF MICROCANTILEVERS -- 5. FABRICATION OF MICROCANTILEVERS -- 6. MICROCANTILEVER-BASED SENSORS -- 6.1 Detection of Biomolecules -- 6.1.1 DNA
- 6.1.2 Prostate-Specific Antigen
Subjects
- Immunoassay.
- Immunologic Tests.
Medical Subject Heading