Effect of a high oxygen concentration on virulence of Staphylococcus aureus

Author / Creator

Schmidt, Jerome P

Available as

Physical

Summary

Cultures of S. aureus were agitated and treated with oxygen or air for a period of 29 days. At intervals of 1, 3, 9, 15, and 29 days, samples of washed cells were tested for coagulase activity and ...

Cultures of S. aureus were agitated and treated with oxygen or air for a period of 29 days. At intervals of 1, 3, 9, 15, and 29 days, samples of washed cells were tested for coagulase activity and for abscess producing ability. It was found that aeration with agitation initially increased abscess formation and that the increase was of the same magnitude for oxygen and air. Throughout the treatment period the bound coagulase activity remained constant. Thus, there appeared to be no quantitative relationship of coagulase titer with virulence as expressed by lesion formation.

Show More