Confronting CJD & other prion disorders : science, sense, support

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Summary

Creutzfeldt-Jakob disease is a mysterious, frightening, devastating illness, with a relentlessly progressive course. Physicians need to know more about CJD: how it occurs, how to make the diagnosis...

Creutzfeldt-Jakob disease is a mysterious, frightening, devastating illness, with a relentlessly progressive course. Physicians need to know more about CJD: how it occurs, how to make the diagnosis, and how to respond when a patient has it. The presentation contains a comprehensive consideration of the different forms of prion disorders: sporadic, familial, and acquired. Clinical features are reviewed through patient presentations and comments by family members. The uses and limitations of various diagnostic tests are presented. Pathogenesis, transmission, and epidemiology are explained.

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