Introduction: from the discovery of biological oxidation to molecular system bioenergetics / Valdur Saks -- Cellular energy metabolism and integrates oxidative phosphorylation / Xavier M. Leverve ... [et. al] -- Organization and regulation of mitochondral oxidative phosphorylation / Michel Rigoulet, Arnaud Mourier, Anne Devin -- Integrated and organized cellular energetic systems: theories of cell energetics, compartmentation, and metabolic channeling / Valdur Saks ... [et.al] -- On the network properties of mitochondria / Miguel A. Aon, Sonia Cortassa, Brian O'Rouke -- Structural organization and dynamics of mitochondria in the cells in Vivo / Andrey V. Kuznetsov -- Mitochondrial VDAC and it complexes / Dieter Brdiczka --The phosphocreatine circuit: molecular and cellular physiology of creatine Kinases, sensitivity to free radicals and enhancement by creatine supplementation / Theo Wallimann ... [et.al] -- Integration of adenlate kinase and glycolytic and glycogenolytic circuits in cellular energetics / Petras P. Dzeja, Susan Chung, Andre Terzic -- Signaling by AMP-activated protein kinase / Dietbert Neumann ... [et. al] -- Developmental and functional consequences of distributed energetic communication in brian of cretine kinase-deficient mice: understanding CK's role in the fuelling of behavior and learning / Femke Streiger ... [et. al] -- System analysis of cardiac energetics-excitation-contraction coupling: integration of mitochondrial repiration, phosphotransfer pathways, metabolic pacing, and substrate supply in the heart / Valdur Saks ... [et. al] -- Principles of mathematical modeling and in silico studies of integrated cellular energetics / Marko Vendelin, Valdur Saks, Jüri Engelbrecht -- Modeling energetics of ion transport, membrane sensing and systems biology of the heart / Satoshi Matsuoko -- Mitochondrial adaptation to exercise and training: a physiological approach / Kent Sahlin -- Mitochondrial medicine: the central role of cellular energetic depression and mitochondria in cell pathophysiology / Enn Seppet ... [et.al] -- Tumor cell energetic metabolome / Sybille Mazurek -- AMPK and the metabolic syndrome / Benoit Viollet, Fabrizo Andreelli -- A systems biology perspective on obesity and type 2 diabetes / Jolita Ciapaite ... [et. al]