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Apoptosis, genomic integrity, and cancer
- Author / Creator
- Available as
- Physical
- Summary
-
Apoptosis, Genomic Integrity and Cancer was written for those working in the medical sciences and in biomedical research, including transnational medicine, cell biology, biochemistry, physiology, p...
Apoptosis, Genomic Integrity and Cancer was written for those working in the medical sciences and in biomedical research, including transnational medicine, cell biology, biochemistry, physiology, pharmacology, experimental pathology, and radiation biology who are engaged in transnational cancer research in particular. The book also provides the oncologist with an understanding of the molecular interactive components that are the foundation of many aspects of diagnosis, prognosis, and therapy.
Details
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- Creator
- Julien L. Van Lancker
- Format
- Books
- Language
- English
- Publication
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- Sudbury, Mass. : Jones and Bartlett Publishers, [2006]
- ©2006
- Physical Details
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- xviii, 422 pages : illustrations ; 26 cm
- ISBNs
- 9780763745417, 0763745413
- OCLC
- ocm60543262
- Includes bibliographical references and index.
- 1. Morphology and occurrence of apoptosis -- 2. Recognition and disposal of the apoptotic bodies -- 3. Agents that trigger apoptosis -- 4. Genes and gene products in apoptosis of C. elegans -- 5. The Bcl-2 family -- 6. Interleukin 1-[beta] converting enzyme (ICE) and caspases -- 7. The cytochrome c-dependent pathway to apoptosis -- 8. Inhibitor of apoptosis proteins (IAPs) -- 9. The p53 gene -- 10. Integrity of the genome and programmed cell death -- 11. Enzymes potentially involved in P53 activation -- 12. P53 and the cell cycle -- 13. Cell cycle checkpoints -- 14. Cell cycle arrest -- 15. P53 transactivation of GADD45 and MDM2 -- 16. The P53 family and apoptosis -- 17. Tumor transforming growth factors and cancer -- 18. Protein tyrosine kinase receptors and cancer -- 19. The oncogenic GTPases -- 20. Non-receptor protein kinases and cancer -- 21. The PIK3/AkT pathway in cancer and apoptosis -- 22. Transcription factors and cancer -- 23. Cancer and genomic instability -- 24. Cancer and genomic instability : mismatch repair and cancer -- 25. Role of Fanconi anemia, breast cancer, and Bloom syndrome genes in oncogenesis -- 26. Cancer and apoptosis
Subjects
- Apoptosis.
- Cancer cells.
- Genomes.
- DNA repair.
- Apoptosis.
Medical Subject Heading
- Cell Cycle -- genetics.
Medical Subject Heading
- DNA Repair.
Medical Subject Heading
- Genome -- genetics.
Medical Subject Heading
- Neoplasms -- genetics.
Medical Subject Heading