Filmmaker Michael Van Laanen presents an unbiased overview of the American stem cell research debate, including a history of the debate, interviews with the general public, researchers, and those personally affected by the research. Dr. James Thomson, the first researcher to embryonic stem cell lines and professor at the University of Wisconsin-Madison, weighs in on the debate and dispels misconceptions about the goals, purposes, and methods of stem cell research. Laboratory technicians at fertilization clinics discuss the process of fertilization, shedding light onto controversies surrounding embryonic stem cell research. Interviews with the public highlight the widespread controversy, ranging from the very religious to a mother who donated her embryos to science. Ultimately, Thomson explains that the vast majority of stem cells are used in drug research, providing a human alternative to animal research in safety and efficacy testing.